Low Dose Heparin

Prophylactic low-dose heparin by jet injection.

graphic deterioration, in the patient and others affected by aerosols of contaminated water in other factories2 3 no radiographic changes were evident after several years' exposure, and no functional abnormalities persisted when away from work. Furthermore, the symptoms were prominent in the early part of the week, improving while continuing at work, but recurring on return to work after an abs...

Heparin for coronary angioplasty: high dose, low dose, or no dose?

Safety of low dose heparin in elective coronary angioplasty.

OBJECTIVES To evaluate the safety of a low dose of heparin in consecutive stable patients undergoing elective percutaneous transluminal coronary angioplasty (PTCA). DESIGN Open prospective study in a single centre. PATIENTS 1375 consecutive patients had elective PTCA (1952 lesions: type A 11%, B1 34%, B2 36%, and C 19%). There were no angiographic exclusion criteria. INTERVENTIONS A bolus...

Unexpectedly high PTT values after low-dose heparin prophylaxis.

T hromboembolic (TE) prophylaxis using lowdose unfractionated heparin (LD-UFH), ie, 5000 IU given subcutaneously twice or 3 times daily is effective, has low bleeding risk, and is generally not expected to prolong partial thromboplastin times (PTTs). Laboratory monitoring or dose adjustments based on weight or renal function are not considered necessary. An index case at our institution prompte...

Complete heparin-coated cardiopulmonary bypass and low heparin dose reduce complement and granulocyte activation.

Complete heparin-coated extracorporeal circuits, including cardiotomy reservoir, have recently become available for routine cardiac surgery. The effects on complement and granulocyte activation using a heparin-coated circuit in combination with reduced systemic heparinization (activated clotting time (ACT) > 250 s) were studied in 33 patients undergoing elective first time myocardial revascular...